Pollo in Guajillo

By Leslie Blythe  , ,   ,

May 31, 2026

Pollo in Guajillo is a traditional Mexican dish featuring chicken thighs that are marinated in a rich, savory sauce made from dried guajillo chiles. Guajillo chiles are known for their smoky, earthy flavor and mild heat making them a popular choice for stews and sauces.

  • Prep: 40 mins
  • Cook: 50 mins
  • Yields: 4 Servings

Ingredients

12 guajillo chiles, stems and seeds removed

½ large white onion, roughly chopped

8 garlic cloves, peeled

¼ teaspoon black peppercorns

1 whole clove

1 tablespoon dried Mexican oregano

2 tablespoons grapeseed oil

¼ cup orange juice

2 tablespoons seasoned rice vinegar

2 tablespoons freshly squeezed lime juice

¼ teaspoon ground cinnamon

1½ tablespoons sea salt

2 pounds bone-in chicken thighs

Directions

1In a cast-iron skillet over medium heat, lightly toast the chiles, about 2 to 3 minutes on each side. Remove from the skillet and set aside.

2
In the same skillet, add the onion and garlic, turning once or twice until they are lightly charred, about 10 minutes. Remove from the skillet and set aside.


3Add the peppercorns, clove, and dried oregano to the pan and lightly toast until they are aromatic, about 2 minutes. Transfer the toasted spices and oregano to a molcajete or spice grinder and grind until finely ground.

4
In a high-performance blender or food processor, add the toasted chiles, onion, garlic, ground spices and oregano, oil, orange juice, rice vinegar, lime juice, cinnamon, and salt. Blend until most of the chiles have come apart.

5Pat the chicken dry with paper towels. Using a gallon-size resealable bag, add the marinade and the chicken. Seal and let sit in the refrigerator for at least 30 minutes or overnight. 


6Remove the chicken thighs in their marinade from the fridge to allow them to reach room temperature before grilling.


7Start a charcoal or gas grill. The gas should be set to high. If using a pellet grill, heat your grill to 450°F for at least 15 minutes. If using charcoal, the coals should be red but entirely covered with gray ash.

8Remove the chicken from the marinade and put them on the grill directly over the medium fire, skin side up. Close the lid and cook, turning once, about 15 minutes on each side. The chicken is cooked when its internal temperature reaches 175°F.

Recipe from Asada, by Bricia Lopez.

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